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Bevantolol hydrochloride
CAS No. 42864-78-8
Bevantolol hydrochloride( NC-1400 hydrochloride )
Catalog No. M21186 CAS No. 42864-78-8
Bevantolol hydrochloride is a β1-adrenoceptor?antagonist that treatment angina pectoris and?hypertension.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 32 | Get Quote |
|
| 25MG | 61 | Get Quote |
|
| 50MG | 87 | Get Quote |
|
| 100MG | 138 | Get Quote |
|
| 200MG | 206 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBevantolol hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionBevantolol hydrochloride is a β1-adrenoceptor?antagonist that treatment angina pectoris and?hypertension.
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DescriptionBevantolol hydrochloride is a β1-adrenoceptor?antagonist that treatment angina pectoris and?hypertension.(In Vitro):Bevantolol hydrochloride has a pKi of 6.23 for β2-adrenergic receptor.(In Vivo):Bevantolol hydrochloride (200 mg/kg; PO by water; for 6 weeks) produces a significant decrease in the expression level of β1 adrenoceptor mRNA.
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In VitroBevantolol hydrochloride has a pKi of 6.23 for β2-adrenergic receptor.
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In VivoBevantolol hydrochloride (200 mg/kg; PO by water; for 6 weeks) produces a significant decrease in the expression level of β1 adrenoceptor mRNA. Animal Model:Male Wistar rats weighing 250-300 g Dosage:200 mg/kg Administration:PO by water; for 6 weeks Result:Produced a significant decrease in the expression level of β1 adrenoceptor mRNA.
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SynonymsNC-1400 hydrochloride
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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Recptorβ1-adrenoceptor
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Research AreaCardiovascular Disease
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IndicationEssential hypertension
Chemical Information
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CAS Number42864-78-8
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Formula Weight381.9
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Molecular FormulaC20H28ClNO4
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Purity>98% (HPLC)
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SolubilityDMSO:76 mg/mL (199.01 mM)Ethanol:61 mg/mL (159.73 mM)H2O:52 mg/mL (136.16 mM)
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SMILESCOc1ccc(CCNCC(O)COc2cccc(C)c2)cc1OC.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Noshiro T Miura Y Yoshinaga K et al. Clinical evaluation of bevantolol hydrochloride in patients with severe hypertension. The Cooperative Study Group on Bevantolol in Japan[J]. International Journal of Clinical Pharmacology & Therapeutics 1995 33(4):240-245.
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